Multinational Observational Cohort Study of COVID-19-Associated Pulmonary Aspergillosis(1)
Nico A. F. Janssen
,
Remy Nyga
(1)
,
Lore Vanderbeke
,
Cato Jacobs
,
Mehmet Ergun
,
Jochem B. Buil
,
Karin Van Dijk
,
Josje Altenburg
,
Catherine S. C. Bouman
,
Hans van Der Spoel
,
Bart J. A. Rijnders
,
Albert Dunbar
,
Jeroen A. Schouten
,
Katrien Lagrou
(2, 3)
,
Marc Bourgeois
(4)
,
Marijke Reynders
,
Niels Van Regenmortel
,
Lynn Rutsaert
,
Piet Lormans
,
Simon Feys
,
Yves Debavaye
,
Fabienne Tamion
(5, 6)
,
Damien Costa
(6)
,
Julien Maizel
(7)
,
Herve Dupont
(8, 7)
,
Taieb Chouaki
(9)
,
Saad Nseir
(10)
,
Boualem Sendid
(10, 11)
,
Roger J. M. Bruggemann
,
Frank L. van De Veerdonk
,
Joost Wauters
(2, 3)
,
Paul E. Verweij
(12)
1
Service de Parasitologie-Mycologie [CHRU LIlle]
2 KU Leuven - Catholic University of Leuven = Katholieke Universiteit Leuven
3 University Hospitals Leuven [Leuven]
4 EVS - Environnement, Ville, Société
5 Hôpital Charles Nicolle [Rouen]
6 CHU Rouen
7 MP3CV - Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517
8 CHU Amiens-Picardie
9 Laboratoire de parasitologie et de mycologie médicales [CHU Amiens]
10 CHU Lille
11 Institut de Microbiologie [CHRU Lille]
12 Radboud University Medical Center [Nijmegen]
2 KU Leuven - Catholic University of Leuven = Katholieke Universiteit Leuven
3 University Hospitals Leuven [Leuven]
4 EVS - Environnement, Ville, Société
5 Hôpital Charles Nicolle [Rouen]
6 CHU Rouen
7 MP3CV - Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517
8 CHU Amiens-Picardie
9 Laboratoire de parasitologie et de mycologie médicales [CHU Amiens]
10 CHU Lille
11 Institut de Microbiologie [CHRU Lille]
12 Radboud University Medical Center [Nijmegen]
Nico A. F. Janssen
- Function : Author
Lore Vanderbeke
- Function : Author
Cato Jacobs
- Function : Author
Mehmet Ergun
- Function : Author
Jochem B. Buil
- Function : Author
Karin Van Dijk
- Function : Author
Josje Altenburg
- Function : Author
Catherine S. C. Bouman
- Function : Author
Hans van Der Spoel
- Function : Author
Bart J. A. Rijnders
- Function : Author
Albert Dunbar
- Function : Author
Jeroen A. Schouten
- Function : Author
Marijke Reynders
- Function : Author
Niels Van Regenmortel
- Function : Author
Lynn Rutsaert
- Function : Author
Piet Lormans
- Function : Author
Simon Feys
- Function : Author
Yves Debavaye
- Function : Author
Damien Costa
- Function : Author
- PersonId : 1156207
- IdHAL : damien-costa
- ORCID : 0000-0003-3418-2597
- IdRef : 187114048
Julien Maizel
- Function : Author
- PersonId : 926124
- ORCID : 0000-0001-5975-2635
- IdRef : 111324203
Herve Dupont
- Function : Author
- PersonId : 913042
- ORCID : 0000-0002-5644-3412
- IdRef : 089058127
Saad Nseir
- Function : Author
- PersonId : 910837
- ORCID : 0000-0002-7618-0357
- IdRef : 103027351
Roger J. M. Bruggemann
- Function : Author
Frank L. van De Veerdonk
- Function : Author
Joost Wauters
- Function : Author
- PersonId : 800853
- ORCID : 0000-0002-5983-3897
Abstract
We performed an observational study to investigate intensive care unit incidence, risk factors, and outcomes of coronavirus disease-associated pulmonary aspergillosis (CAPA). We found 10%-15% CAPA incidence among 823 patients in 2 cohorts. Several factors were independently associated with CAPA in 1 cohort and mortality rates were 43%-52%.